2er8

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[[Image:2er8.png|left|200px]]
 
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{{STRUCTURE_2er8| PDB=2er8 | SCENE= }}
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==Crystal Structure of Leu3 DNA-binding domain complexed with a 12mer DNA duplex==
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<StructureSection load='2er8' size='340' side='right'caption='[[2er8]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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===Crystal Structure of Leu3 DNA-binding domain complexed with a 12mer DNA duplex===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2er8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ER8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ER8 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16615914}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2er8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2er8 OCA], [https://pdbe.org/2er8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2er8 RCSB], [https://www.ebi.ac.uk/pdbsum/2er8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2er8 ProSAT]</span></td></tr>
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[[2er8]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ER8 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/LEUR_YEAST LEUR_YEAST] Factor for control of RNA levels of a group of leucine-specific genes.
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<ref group="xtra">PMID:016615914</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/er/2er8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2er8 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Fitzgerald, M X.]]
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[[Category: Fitzgerald MX]]
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[[Category: Marmorstein, R.]]
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[[Category: Marmorstein R]]
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[[Category: Transcription activator-dna complex]]
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Current revision

Crystal Structure of Leu3 DNA-binding domain complexed with a 12mer DNA duplex

PDB ID 2er8

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