2ex3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:20, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2ex3.png|left|200px]]
 
-
<!--
+
==Bacteriophage phi29 DNA polymerase bound to terminal protein==
-
The line below this paragraph, containing "STRUCTURE_2ex3", creates the "Structure Box" on the page.
+
<StructureSection load='2ex3' size='340' side='right'caption='[[2ex3]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2ex3]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_virus_phi29 Bacillus virus phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EX3 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene></td></tr>
-
{{STRUCTURE_2ex3| PDB=2ex3 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ex3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ex3 OCA], [https://pdbe.org/2ex3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ex3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ex3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ex3 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DPOL_BPPH2 DPOL_BPPH2] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/2ex3_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ex3 ConSurf].
 +
<div style="clear:both"></div>
-
===Bacteriophage phi29 DNA polymerase bound to terminal protein===
+
==See Also==
-
 
+
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_16511564}}, adds the Publication Abstract to the page
+
[[Category: Bacillus virus phi29]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 16511564 is the PubMed ID number.
+
[[Category: Large Structures]]
-
-->
+
[[Category: Berman AJ]]
-
{{ABSTRACT_PUBMED_16511564}}
+
[[Category: Blanco L]]
-
 
+
[[Category: Kamtekar S]]
-
==About this Structure==
+
[[Category: Salas M]]
-
2EX3 is a 12 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_phage_phi29 Bacillus phage phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EX3 OCA].
+
[[Category: Steitz TA]]
-
 
+
[[Category: Wang J]]
-
==Reference==
+
[[Category: De Vega M]]
-
<ref group="xtra">PMID:16511564</ref><references group="xtra"/>
+
-
[[Category: Bacillus phage phi29]]
+
-
[[Category: DNA-directed DNA polymerase]]
+
-
[[Category: Berman, A J.]]
+
-
[[Category: Blanco, L.]]
+
-
[[Category: Kamtekar, S.]]
+
-
[[Category: Salas, M.]]
+
-
[[Category: Steitz, T A.]]
+
-
[[Category: Vega, M de.]]
+
-
[[Category: Wang, J.]]
+
-
[[Category: Dna polymerase: protein primer complex]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:06:03 2009''
+

Current revision

Bacteriophage phi29 DNA polymerase bound to terminal protein

PDB ID 2ex3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools