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2f3d

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[[Image:2f3d.png|left|200px]]
 
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==Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase==
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The line below this paragraph, containing "STRUCTURE_2f3d", creates the "Structure Box" on the page.
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<StructureSection load='2f3d' size='340' side='right'caption='[[2f3d]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2f3d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F3D FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2f3d| PDB=2f3d | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f3d OCA], [https://pdbe.org/2f3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f3d RCSB], [https://www.ebi.ac.uk/pdbsum/2f3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f3d ProSAT]</span></td></tr>
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</table>
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===Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase===
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== Function ==
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[https://www.uniprot.org/uniprot/F16P1_PIG F16P1_PIG]
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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[[2f3d]] is a 1 chain structure of [[Fructose-1%2C6-bisphosphatase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F3D OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f3/2f3d_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f3d ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Fructose-1%2C6-bisphosphatase]]
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*[[Fructose-1%2C6-bisphosphatase 3D structures|Fructose-1%2C6-bisphosphatase 3D structures]]
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[[Category: Fructose-bisphosphatase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Choe, J Y.]]
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[[Category: Choe J-Y]]
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[[Category: Fromm, H J.]]
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[[Category: Fromm HJ]]
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[[Category: Honzatko, R B.]]
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[[Category: Honzatko RB]]
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[[Category: Iancu, C V.]]
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[[Category: Iancu CV]]
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[[Category: Mukund, S.]]
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[[Category: Mukund S]]
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[[Category: 6-bisphosphatase]]
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[[Category: Allosteric regulation]]
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[[Category: Allostery]]
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[[Category: Enzyme catalysis]]
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[[Category: Fbpase]]
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[[Category: Fructose-1]]
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[[Category: Hydrolase]]
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[[Category: Loop displacement]]
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Current revision

Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase

PDB ID 2f3d

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