2fhs

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{{Seed}}
 
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[[Image:2fhs.png|left|200px]]
 
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==Structure of Acyl Carrier Protein Bound to FabI, the Enoyl Reductase from Escherichia Coli==
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The line below this paragraph, containing "STRUCTURE_2fhs", creates the "Structure Box" on the page.
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<StructureSection load='2fhs' size='340' side='right'caption='[[2fhs]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fhs]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._W3110 Escherichia coli str. K-12 substr. W3110]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FHS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fhs OCA], [https://pdbe.org/2fhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fhs RCSB], [https://www.ebi.ac.uk/pdbsum/2fhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fhs ProSAT]</span></td></tr>
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{{STRUCTURE_2fhs| PDB=2fhs | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABI_ECOLI FABI_ECOLI] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.<ref>PMID:8119879</ref> <ref>PMID:7592873</ref> <ref>PMID:20693992</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fh/2fhs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fhs ConSurf].
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<div style="clear:both"></div>
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===Structure of Acyl Carrier Protein Bound to FabI, the Enoyl Reductase from Escherichia Coli===
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==See Also==
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*[[Acyl carrier protein 3D structures|Acyl carrier protein 3D structures]]
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*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
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== References ==
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The line below this paragraph, {{ABSTRACT_PUBMED_17012233}}, adds the Publication Abstract to the page
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 17012233 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_17012233}}
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==About this Structure==
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2FHS is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Escherichia_coli_w3110 Escherichia coli w3110]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FHS OCA].
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==Reference==
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Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli., Rafi S, Novichenok P, Kolappan S, Zhang X, Stratton CF, Rawat R, Kisker C, Simmerling C, Tonge PJ, J Biol Chem. 2006 Dec 22;281(51):39285-93. Epub 2006 Sep 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17012233 17012233]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Escherichia coli w3110]]
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[[Category: Escherichia coli str. K-12 substr. W3110]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Kisker, C.]]
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[[Category: Kisker C]]
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[[Category: Kolappan, S.]]
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[[Category: Kolappan S]]
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[[Category: Novichenok, P.]]
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[[Category: Novichenok P]]
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[[Category: Rafi, S.]]
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[[Category: Rafi S]]
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[[Category: Simmerling, C.]]
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[[Category: Simmerling C]]
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[[Category: Tonge, P J.]]
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[[Category: Tonge PJ]]
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[[Category: Protein-protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:41:43 2008''
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Current revision

Structure of Acyl Carrier Protein Bound to FabI, the Enoyl Reductase from Escherichia Coli

PDB ID 2fhs

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