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2fkk

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[[Image:2fkk.png|left|200px]]
 
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{{STRUCTURE_2fkk| PDB=2fkk | SCENE= }}
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==Crystal structure of the C-terminal domain of the bacteriophage T4 gene product 10==
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<StructureSection load='2fkk' size='340' side='right'caption='[[2fkk]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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===Crystal structure of the C-terminal domain of the bacteriophage T4 gene product 10===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2fkk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FKK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16554069}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO3:PHOSPHITE+ION'>PO3</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fkk OCA], [https://pdbe.org/2fkk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fkk RCSB], [https://www.ebi.ac.uk/pdbsum/2fkk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fkk ProSAT]</span></td></tr>
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[[2fkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKK OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/BP10_BPT4 BP10_BPT4] Baseplate protein that is part of the baseplate wedge and that connects the short tail fibers to the baseplate (PubMed:16554069). During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors. Involved in the tail assembly.<ref>PMID:16554069</ref> <ref>PMID:21129200</ref>
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<ref group="xtra">PMID:016554069</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Enterobacteria phage t4]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Leiman, P G.]]
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Check<jmol>
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[[Category: Mesyanzhinov, V V.]]
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<jmolCheckbox>
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[[Category: Rossmann, M G.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fk/2fkk_consurf.spt"</scriptWhenChecked>
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[[Category: Shneider, M M.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Bacteriophage t4]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Baseplate]]
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</jmolCheckbox>
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[[Category: Evolution]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fkk ConSurf].
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[[Category: Gp10]]
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<div style="clear:both"></div>
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[[Category: Structural comparison]]
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== References ==
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[[Category: Tail]]
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<references/>
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[[Category: Viral protein]]
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__TOC__
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</StructureSection>
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[[Category: Escherichia virus T4]]
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[[Category: Large Structures]]
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[[Category: Leiman PG]]
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[[Category: Mesyanzhinov VV]]
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[[Category: Rossmann MG]]
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[[Category: Shneider MM]]

Current revision

Crystal structure of the C-terminal domain of the bacteriophage T4 gene product 10

PDB ID 2fkk

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