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2fnu

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{{Seed}}
 
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[[Image:2fnu.png|left|200px]]
 
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==PseC aminotransferase with external aldimine==
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The line below this paragraph, containing "STRUCTURE_2fnu", creates the "Structure Box" on the page.
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<StructureSection load='2fnu' size='340' side='right'caption='[[2fnu]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fnu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FNU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr>
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{{STRUCTURE_2fnu| PDB=2fnu | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fnu OCA], [https://pdbe.org/2fnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fnu RCSB], [https://www.ebi.ac.uk/pdbsum/2fnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fnu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PSEC_HELPY PSEC_HELPY] Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L-AltNAc.<ref>PMID:16286454</ref> <ref>PMID:16421095</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/2fnu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fnu ConSurf].
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<div style="clear:both"></div>
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===PseC aminotransferase with external aldimine===
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==See Also==
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*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 16421095 is the PubMed ID number.
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</StructureSection>
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[[Category: Helicobacter pylori 26695]]
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{{ABSTRACT_PUBMED_16421095}}
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[[Category: Large Structures]]
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[[Category: Cygler M]]
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==About this Structure==
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[[Category: Matte A]]
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2FNU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FNU OCA].
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==Reference==
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Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori., Schoenhofen IC, Lunin VV, Julien JP, Li Y, Ajamian E, Matte A, Cygler M, Brisson JR, Aubry A, Logan SM, Bhatia S, Wakarchuk WW, Young NM, J Biol Chem. 2006 Mar 31;281(13):8907-16. Epub 2006 Jan 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16421095 16421095]
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[[Category: Helicobacter pylori]]
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[[Category: Single protein]]
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[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
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[[Category: Cygler, M.]]
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[[Category: Matte, A.]]
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[[Category: Bsgi]]
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
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[[Category: Protein-product complex]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:12:23 2008''
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Current revision

PseC aminotransferase with external aldimine

PDB ID 2fnu

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