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2g37

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{{Seed}}
 
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[[Image:2g37.png|left|200px]]
 
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<!--
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==Structure of Thermus thermophilus L-proline dehydrogenase==
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The line below this paragraph, containing "STRUCTURE_2g37", creates the "Structure Box" on the page.
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<StructureSection load='2g37' size='340' side='right'caption='[[2g37]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2g37]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G37 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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{{STRUCTURE_2g37| PDB=2g37 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g37 OCA], [https://pdbe.org/2g37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g37 RCSB], [https://www.ebi.ac.uk/pdbsum/2g37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g37 ProSAT]</span></td></tr>
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</table>
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===Structure of Thermus thermophilus L-proline dehydrogenase===
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== Function ==
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[https://www.uniprot.org/uniprot/PRODH_THET2 PRODH_THET2] Converts proline to delta-1-pyrroline-5-carboxylate (PubMed:17344208, PubMed:18426222). Has significant activity against O(2) producing superoxide during proline oxidation catalytic cycle (PubMed:17344208).<ref>PMID:17344208</ref> <ref>PMID:18426222</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17344208 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/2g37_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17344208}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2G37 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb27 Thermus thermophilus hb27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G37 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g37 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:17344208</ref><references group="xtra"/>
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<references/>
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[[Category: Proline dehydrogenase]]
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__TOC__
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[[Category: Thermus thermophilus hb27]]
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</StructureSection>
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[[Category: Tanner, J J.]]
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[[Category: Large Structures]]
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[[Category: White, T A.]]
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[[Category: Thermus thermophilus HB27]]
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[[Category: Beta8-alpha8-barrel]]
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[[Category: Tanner JJ]]
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[[Category: Flavoenzyme]]
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[[Category: White TA]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Apr 19 08:39:28 2009''
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Current revision

Structure of Thermus thermophilus L-proline dehydrogenase

PDB ID 2g37

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