2hqc

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{{Seed}}
 
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[[Image:2hqc.png|left|200px]]
 
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<!--
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==Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway==
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The line below this paragraph, containing "STRUCTURE_2hqc", creates the "Structure Box" on the page.
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<StructureSection load='2hqc' size='340' side='right'caption='[[2hqc]], [[Resolution|resolution]] 3.56&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2hqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.56&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqc OCA], [https://pdbe.org/2hqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqc RCSB], [https://www.ebi.ac.uk/pdbsum/2hqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqc ProSAT]</span></td></tr>
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{{STRUCTURE_2hqc| PDB=2hqc | SCENE= }}
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</table>
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== Function ==
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===Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway===
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[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_17015668}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 17015668 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/2hqc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_17015668}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hqc ConSurf].
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2HQC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQC OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:17015668</ref><references group="xtra"/>
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__TOC__
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[[Category: Escherichia coli]]
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</StructureSection>
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[[Category: Gu, R.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Li, M.]]
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[[Category: Large Structures]]
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[[Category: McDermott, G.]]
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[[Category: Gu R]]
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[[Category: Nikaido, H.]]
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[[Category: Li M]]
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[[Category: Su, C C.]]
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[[Category: McDermott G]]
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[[Category: Takatsuka, Y.]]
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[[Category: Nikaido H]]
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[[Category: Yu, E W.]]
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[[Category: Su C-C]]
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[[Category: Membrane protein]]
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[[Category: Takatsuka Y]]
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[[Category: Multidrug efflux pump]]
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[[Category: Yu EW]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:36:02 2009''
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Current revision

Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway

PDB ID 2hqc

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