This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2hrw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2hrw" [edit=sysop:move=sysop])
Current revision (09:34, 14 February 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2hrw.png|left|200px]]
 
-
{{STRUCTURE_2hrw| PDB=2hrw | SCENE= }}
+
==Crystal Structure of Phosphonopyruvate Hydrolase==
-
 
+
<StructureSection load='2hrw' size='340' side='right'caption='[[2hrw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
===Crystal Structure of Phosphonopyruvate Hydrolase===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2hrw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Variovorax_sp._Pal2 Variovorax sp. Pal2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HRW FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_16981709}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hrw OCA], [https://pdbe.org/2hrw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hrw RCSB], [https://www.ebi.ac.uk/pdbsum/2hrw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hrw ProSAT]</span></td></tr>
-
[[2hrw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Variovorax_sp._pal2 Variovorax sp. pal2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRW OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/PPHA_VARSP PPHA_VARSP] Hydrolyzes phosphonopyruvate. Not active towards phosphoenolpyruvate, glycerophosphate, phospho-L-serine or phosphoglycolic acid.<ref>PMID:12697754</ref>
-
<ref group="xtra">PMID:016981709</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
-
[[Category: Variovorax sp. pal2]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Chen, C C.H.]]
+
Check<jmol>
-
[[Category: Herzberg, O.]]
+
<jmolCheckbox>
-
[[Category: Hydrolase]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hr/2hrw_consurf.spt"</scriptWhenChecked>
-
[[Category: Pep mutase/isocitrate lyase superfamily]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Phosphonopyruvate]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Phosphonopyruvate hydrolase]]
+
</jmolCheckbox>
-
[[Category: Phosphorus-carbon bond cleavage]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hrw ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Variovorax sp. Pal2]]
 +
[[Category: Chen CCH]]
 +
[[Category: Herzberg O]]

Current revision

Crystal Structure of Phosphonopyruvate Hydrolase

PDB ID 2hrw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools