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7uy7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Tetrahymena CST with Polymerase alpha-Primase== | |
| + | <StructureSection load='7uy7' size='340' side='right'caption='[[7uy7]], [[Resolution|resolution]] 4.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7uy7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UY7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uy7 OCA], [https://pdbe.org/7uy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uy7 RCSB], [https://www.ebi.ac.uk/pdbsum/7uy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uy7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TAP19_TETTS TAP19_TETTS] Component of a CST-like subcomplex of the holoenzyme telomerase ribonucleoprotein complex, which stimulates telomerase complementary-strand synthesis (PubMed:26551074). Telomerase is an essential ribonucleoprotein enzyme that copies new telomeric repeats onto chromosome ends by repetitively synthesizing the short telomere-repeat sequence 5'-TTGGGG-3' using an RNA template component TER (PubMed:26551074). The CST-like subcomplex (also named 7-4-1) binds telomeric single-stranded DNA and coordinates telomere G-strand and C-strand synthesis (PubMed:26551074).<ref>PMID:26551074</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |
| - | + | *[[Telomerase 3D structures|Telomerase 3D structures]] | |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Tetrahymena thermophila]] | ||
| + | [[Category: Chan H]] | ||
| + | [[Category: Feigon J]] | ||
| + | [[Category: He Y]] | ||
| + | [[Category: Liu B]] | ||
| + | [[Category: Song H]] | ||
| + | [[Category: Susac L]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Zhou ZH]] | ||
Current revision
Tetrahymena CST with Polymerase alpha-Primase
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Categories: Large Structures | Tetrahymena thermophila | Chan H | Feigon J | He Y | Liu B | Song H | Susac L | Wang Y | Zhou ZH
