3bna

<StructureSection load='3bna' size='340' side='right' caption='[[3bna]], [[Resolution|resolution]] 3.00&Aring;' scene=''>

<table><tr><td colspan='2'>[[3bna]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BNA FirstGlance]. <br>

</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bna OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bna RCSB], [http://www.ebi.ac.uk/pdbsum/3bna PDBsum]</span></td></tr>

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== Publication Abstract from PubMed ==

A double-helical B-DNA dodecamer has been analyzed by single crystal x-ray diffraction methods and refined independently in four variants: sequence CGCGAATTCGCG at 20 degrees C and at 16 K, and CGCGAATTBrCGCG in 60% methylpentanediol at 20 and at 7 degrees C. The first three forms show a 14-19 degrees bend in overall helix axis, but the fourth is straight and unbent. Detailed comparisons of the various forms have led to a better understanding of helix geometry and bending. Structural principles can be understood best if organized under four headings: 1) intrinsic geometry of the sugar rings, 2) stacking and relative motion of base pairs, 3) geometry of the connecting phosphate backbone, and 4) mechanics of bending in B-DNA. The observed bending is neither completely localized nor smooth and continuous, but an intermediate compromise that can be termed "annealed kinking."

Reversible bending and helix geometry in a B-DNA dodecamer: CGCGAATTBrCGCG.,Fratini AV, Kopka ML, Drew HR, Dickerson RE J Biol Chem. 1982 Dec 25;257(24):14686-707. PMID:7174662<ref>PMID:7174662</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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== References ==

<references/>

[[Category: Dickerson, R E.]]

[[Category: Fratini, A V.]]

[[Category: Kopka, M L.]]

[[Category: B-dna]]

[[Category: Modified]]