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3n87
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 3== | |
| + | <StructureSection load='3n87' size='340' side='right'caption='[[3n87]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3n87]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N87 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N87:(1R,4R,5R)-1,4,5-TRIHYDROXY-3-[3-(PHENYLCARBONYL)PHENYL]CYCLOHEX-2-ENE-1-CARBOXYLIC+ACID'>N87</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n87 OCA], [https://pdbe.org/3n87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n87 RCSB], [https://www.ebi.ac.uk/pdbsum/3n87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n87 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169] | ||
| - | + | ==See Also== | |
| - | + | *[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Abell C]] | ||
| + | [[Category: Blundell TL]] | ||
| + | [[Category: Bromfield KM]] | ||
| + | [[Category: Ciulli A]] | ||
| + | [[Category: Dias MVB]] | ||
| + | [[Category: Howard NI]] | ||
| + | [[Category: Palaninathan SK]] | ||
| + | [[Category: Payne R]] | ||
| + | [[Category: Sacchettini JC]] | ||
| + | [[Category: Snee WC]] | ||
Current revision
Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 3
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