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3n87

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[[Image:3n87.png|left|200px]]
 
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==Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 3==
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The line below this paragraph, containing "STRUCTURE_3n87", creates the "Structure Box" on the page.
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<StructureSection load='3n87' size='340' side='right'caption='[[3n87]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3n87]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N87 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N87:(1R,4R,5R)-1,4,5-TRIHYDROXY-3-[3-(PHENYLCARBONYL)PHENYL]CYCLOHEX-2-ENE-1-CARBOXYLIC+ACID'>N87</scene></td></tr>
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{{STRUCTURE_3n87| PDB=3n87 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n87 OCA], [https://pdbe.org/3n87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n87 RCSB], [https://www.ebi.ac.uk/pdbsum/3n87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n87 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
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===Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 3===
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==See Also==
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*[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_21410435}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21410435 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21410435}}
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==About this Structure==
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[[3n87]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N87 OCA].
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==Reference==
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<ref group="xtra">PMID:021410435</ref><references group="xtra"/>
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[[Category: 3-dehydroquinate dehydratase]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Abell, C.]]
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[[Category: Blundell, T L.]]
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[[Category: Bromfield, K M.]]
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[[Category: Ciulli, A.]]
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[[Category: Dias, M V.B.]]
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[[Category: Howard, N I.]]
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[[Category: Palaninathan, S K.]]
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[[Category: Payne, R.]]
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[[Category: Sacchettini, J C.]]
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[[Category: Snee, W C.]]
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[[Category: Arod]]
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[[Category: Dehydroquinate dehydratase]]
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[[Category: Drug discovery]]
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[[Category: Lyase]]
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[[Category: Lyase-lyase inhibitor complex]]
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[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Shikimate pathway]]
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[[Category: Abell C]]
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[[Category: Blundell TL]]
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[[Category: Bromfield KM]]
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[[Category: Ciulli A]]
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[[Category: Dias MVB]]
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[[Category: Howard NI]]
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[[Category: Palaninathan SK]]
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[[Category: Payne R]]
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[[Category: Sacchettini JC]]
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[[Category: Snee WC]]

Current revision

Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 3

PDB ID 3n87

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