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3nh8
From Proteopedia
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| - | [[Image:3nh8.png|left|200px]] | ||
| - | + | ==Crystal structure of murine aminoacylase 3 in complex with N-acetyl-S-1,2-dichlorovinyl-L-cysteine== | |
| - | + | <StructureSection load='3nh8' size='340' side='right'caption='[[3nh8]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3nh8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NH8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.802Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DC2:N-ACETYL-S-[(1S)-1,2-DICHLOROETHYL]-L-CYSTEINE'>DC2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nh8 OCA], [https://pdbe.org/3nh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nh8 RCSB], [https://www.ebi.ac.uk/pdbsum/3nh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nh8 ProSAT]</span></td></tr> |
| - | [[3nh8]] is a 1 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACY3_MOUSE ACY3_MOUSE] Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids.<ref>PMID:14656720</ref> <ref>PMID:17012540</ref> | ||
==See Also== | ==See Also== | ||
| - | *[[Aspartoacylase|Aspartoacylase]] | + | *[[Aminoacylase 3D structures|Aminoacylase 3D structures]] |
| - | + | *[[Aspartoacylase 3D structures|Aspartoacylase 3D structures]] | |
| - | == | + | == References == |
| - | < | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Abramson | + | [[Category: Abramson J]] |
| - | [[Category: Abuladze | + | [[Category: Abuladze N]] |
| - | [[Category: Hsieh | + | [[Category: Hsieh JM]] |
| - | [[Category: Kurtz | + | [[Category: Kurtz I]] |
| - | [[Category: Magilnick | + | [[Category: Magilnick N]] |
| - | [[Category: Pushkin | + | [[Category: Pushkin A]] |
| - | [[Category: Sawaya | + | [[Category: Sawaya MR]] |
| - | [[Category: Tsirulnikov | + | [[Category: Tsirulnikov K]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of murine aminoacylase 3 in complex with N-acetyl-S-1,2-dichlorovinyl-L-cysteine
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Categories: Large Structures | Mus musculus | Abramson J | Abuladze N | Hsieh JM | Kurtz I | Magilnick N | Pushkin A | Sawaya MR | Tsirulnikov K
