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8cgy
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing== | |
| - | + | <StructureSection load='8cgy' size='340' side='right'caption='[[8cgy]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8cgy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CGY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cgy OCA], [https://pdbe.org/8cgy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cgy RCSB], [https://www.ebi.ac.uk/pdbsum/8cgy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cgy ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IMDH_TRYBB IMDH_TRYBB] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Trypanosoma brucei]] | ||
| + | [[Category: Boger J]] | ||
| + | [[Category: Bourenkov G]] | ||
| + | [[Category: Duden R]] | ||
| + | [[Category: Harms M]] | ||
| + | [[Category: Kaiser J]] | ||
| + | [[Category: Lahey-Rudolph JM]] | ||
| + | [[Category: Nachtschatt S]] | ||
| + | [[Category: Redecke L]] | ||
| + | [[Category: Schneider T]] | ||
| + | [[Category: Schoenherr R]] | ||
| + | [[Category: Wobbe M]] | ||
Current revision
Trypanosoma brucei IMP dehydrogenase (ori) crystallized in High Five cells reveals native ligands ATP, GDP and phosphate. Diffraction data collection at 100 K in cellulo; XDS processing
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Categories: Large Structures | Trypanosoma brucei | Boger J | Bourenkov G | Duden R | Harms M | Kaiser J | Lahey-Rudolph JM | Nachtschatt S | Redecke L | Schneider T | Schoenherr R | Wobbe M
