2i2x
From Proteopedia
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| - | [[Image:2i2x.gif|left|200px]]<br /><applet load="2i2x" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2i2x, resolution 2.50Å" /> | ||
| - | '''Crystal structure of methanol:cobalamin methyltransferase complex MtaBC from Methanosarcina barkeri'''<br /> | ||
| - | == | + | ==Crystal structure of methanol:cobalamin methyltransferase complex MtaBC from Methanosarcina barkeri== |
| - | + | <StructureSection load='2i2x' size='340' side='right'caption='[[2i2x]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | [[Category: | + | == Structural highlights == |
| + | <table><tr><td colspan='2'>[[2i2x]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_barkeri Methanosarcina barkeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I2X FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B13:5-HYDROXYBENZIMIDAZOLYLCOB(III)AMIDE'>B13</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i2x OCA], [https://pdbe.org/2i2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i2x RCSB], [https://www.ebi.ac.uk/pdbsum/2i2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i2x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MTAB_METBF MTAB_METBF] Methyltransferase involved in methanogenesis in the methanol pathway. Catalyzes the methylation of the MtaC-bound cob(I)amide.<ref>PMID:9057830</ref> <ref>PMID:9363780</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/2i2x_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i2x ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Methanosarcina barkeri]] | [[Category: Methanosarcina barkeri]] | ||
| - | + | [[Category: Ermler U]] | |
| - | [[Category: Ermler | + | [[Category: Hagemeier CH]] |
| - | [[Category: Hagemeier | + | [[Category: Kruer M]] |
| - | [[Category: Kruer | + | [[Category: Thauer RK]] |
| - | [[Category: Thauer | + | [[Category: Warkentin E]] |
| - | [[Category: Warkentin | + | |
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Current revision
Crystal structure of methanol:cobalamin methyltransferase complex MtaBC from Methanosarcina barkeri
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