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2i8u

From Proteopedia

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[[Image:2i8u.png|left|200px]]
 
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{{STRUCTURE_2i8u| PDB=2i8u | SCENE= }}
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==GDP-mannose mannosyl hydrolase-calcium-GDP product complex==
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<StructureSection load='2i8u' size='340' side='right'caption='[[2i8u]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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===GDP-mannose mannosyl hydrolase-calcium-GDP product complex===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2i8u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I8U FirstGlance]. <br>
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{{ABSTRACT_PUBMED_17371001}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i8u OCA], [https://pdbe.org/2i8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i8u RCSB], [https://www.ebi.ac.uk/pdbsum/2i8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i8u ProSAT]</span></td></tr>
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[[2i8u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I8U OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/Q6XQ58_ECOLX Q6XQ58_ECOLX] Hydrolyzes GDP-mannose.[HAMAP-Rule:MF_00941]
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<ref group="xtra">PMID:017371001</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/2i8u_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i8u ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Brunzelle, J S.]]
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[[Category: Large Structures]]
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[[Category: Li, C.]]
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[[Category: Brunzelle JS]]
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[[Category: Nair, S K.]]
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[[Category: Li C]]
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[[Category: Zou, Y.]]
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[[Category: Nair SK]]
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[[Category: Hydrolase]]
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[[Category: Zou Y]]
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[[Category: Lipopolysaccharide]]
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[[Category: Nudix enzyme]]
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Current revision

GDP-mannose mannosyl hydrolase-calcium-GDP product complex

PDB ID 2i8u

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