This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2osz
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2osz.png|left|200px]] | ||
| - | + | ==Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding== | |
| - | + | <StructureSection load='2osz' size='340' side='right'caption='[[2osz]], [[Resolution|resolution]] 2.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2osz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OSZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OSZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2osz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2osz OCA], [https://pdbe.org/2osz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2osz RCSB], [https://www.ebi.ac.uk/pdbsum/2osz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2osz ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[2osz]] is a 4 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/NUP58_RAT NUP58_RAT] Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.<ref>PMID:8707840</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/2osz_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2osz ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Nucleoporin|Nucleoporin]] | + | *[[Nucleoporin 3D structures|Nucleoporin 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Blobel | + | [[Category: Blobel G]] |
| - | [[Category: Hoelz | + | [[Category: Hoelz A]] |
| - | [[Category: Melcak | + | [[Category: Melcak I]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding
| |||||||||||
