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2p1j

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[[Image:2p1j.png|left|200px]]
 
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{{STRUCTURE_2p1j| PDB=2p1j | SCENE= }}
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==Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima==
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<StructureSection load='2p1j' size='340' side='right'caption='[[2p1j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2p1j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P1J FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p1j OCA], [https://pdbe.org/2p1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p1j RCSB], [https://www.ebi.ac.uk/pdbsum/2p1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p1j ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2p1j TOPSAN]</span></td></tr>
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[[2p1j]] is a 2 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P1J OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPO3_THEMA DPO3_THEMA] Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p1/2p1j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p1j ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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[[Category: DNA-directed DNA polymerase]]
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__TOC__
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[[Category: Thermotoga maritima msb8]]
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</StructureSection>
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[[Category: Almo, S C.]]
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[[Category: Large Structures]]
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[[Category: Bain, K T.]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Bonanno, J B.]]
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[[Category: Almo SC]]
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[[Category: Burley, S K.]]
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[[Category: Bain KT]]
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[[Category: Izuka, M.]]
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[[Category: Bonanno JB]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Burley SK]]
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[[Category: Rutter, M.]]
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[[Category: Izuka M]]
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[[Category: Sauder, M J.]]
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[[Category: Rutter M]]
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[[Category: Smith, D.]]
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[[Category: Sauder JM]]
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[[Category: Sridhar, V.]]
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[[Category: Smith D]]
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[[Category: Wasserman, S.]]
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[[Category: Sridhar V]]
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[[Category: Exonuclease]]
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[[Category: Wasserman S]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: Nysgxrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima

PDB ID 2p1j

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