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2p5u

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[[Image:2p5u.gif|left|200px]]<br /><applet load="2p5u" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2p5u, resolution 2.370&Aring;" />
 
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'''Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD'''<br />
 
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==About this Structure==
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==Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD==
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2P5U is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/UDP-glucose_4-epimerase UDP-glucose 4-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.2 5.1.3.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5U OCA].
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<StructureSection load='2p5u' size='340' side='right'caption='[[2p5u]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
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[[Category: Single protein]]
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== Structural highlights ==
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[[Category: Thermus thermophilus]]
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<table><tr><td colspan='2'>[[2p5u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P5U FirstGlance]. <br>
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[[Category: UDP-glucose 4-epimerase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
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[[Category: Chen, L.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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[[Category: Chrzas, J.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5u OCA], [https://pdbe.org/2p5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p5u RCSB], [https://www.ebi.ac.uk/pdbsum/2p5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p5u ProSAT], [https://www.topsan.org/Proteins/RSGI/2p5u TOPSAN]</span></td></tr>
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[[Category: Dillard, B.]]
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</table>
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[[Category: Ebihara, A.]]
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== Function ==
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[[Category: Fu, Z-Q.]]
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[https://www.uniprot.org/uniprot/Q5SKQ2_THET8 Q5SKQ2_THET8]
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[[Category: Kuramitsu, S.]]
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== Evolutionary Conservation ==
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Rose, J P.]]
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Check<jmol>
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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<jmolCheckbox>
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[[Category: Shinkai, A.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p5/2p5u_consurf.spt"</scriptWhenChecked>
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[[Category: Wang, B-C.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Yokoyama, S.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Zhao, M.]]
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</jmolCheckbox>
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[[Category: NAD]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p5u ConSurf].
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[[Category: national project on protein structural and functional analyses]]
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<div style="clear:both"></div>
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[[Category: nppsfa]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: secsg]]
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[[Category: southeast collaboratory for structural genomics]]
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[[Category: structural genomics]]
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[[Category: thermus thermophilus hb8]]
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[[Category: ttha0591]]
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[[Category: udp-glucose 4-epimerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:26:12 2008''
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==See Also==
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*[[UDP-galactose 4-epimerase|UDP-galactose 4-epimerase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Chen L]]
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[[Category: Chrzas J]]
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[[Category: Dillard B]]
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[[Category: Ebihara A]]
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[[Category: Fu Z-Q]]
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[[Category: Kuramitsu S]]
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[[Category: Rose JP]]
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[[Category: Shinkai A]]
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[[Category: Wang B-C]]
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[[Category: Yokoyama S]]
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[[Category: Zhao M]]

Current revision

Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD

PDB ID 2p5u

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