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2q91

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{{Seed}}
 
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[[Image:2q91.png|left|200px]]
 
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==Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor==
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The line below this paragraph, containing "STRUCTURE_2q91", creates the "Structure Box" on the page.
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<StructureSection load='2q91' size='340' side='right'caption='[[2q91]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2q91]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q91 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_2q91| PDB=2q91 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q91 OCA], [https://pdbe.org/2q91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q91 RCSB], [https://www.ebi.ac.uk/pdbsum/2q91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q91 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S10A4_HUMAN S10A4_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/2q91_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q91 ConSurf].
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<div style="clear:both"></div>
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===Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor===
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==See Also==
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*[[S100 proteins 3D structures|S100 proteins 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18410126}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 18410126 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18410126}}
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==About this Structure==
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2Q91 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q91 OCA].
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==Reference==
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Structure of Ca(2+)-Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA., Malashkevich VN, Varney KM, Garrett SC, Wilder PT, Knight D, Charpentier TH, Ramagopal UA, Almo SC, Weber DJ, Bresnick AR, Biochemistry. 2008 May 6;47(18):5111-5126. Epub 2008 Apr 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18410126 18410126]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Bresnick, A R.]]
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[[Category: Bresnick AR]]
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[[Category: Knight, D.]]
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[[Category: Knight D]]
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[[Category: Malashkevich, V N.]]
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[[Category: Malashkevich VN]]
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[[Category: Ramagopal, U A.]]
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[[Category: Ramagopal UA]]
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[[Category: Calcium]]
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[[Category: Ef-hand]]
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[[Category: Metal binding protein]]
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[[Category: Metastatic tumor]]
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[[Category: Myosin]]
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[[Category: S100a4]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:43:36 2008''
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Current revision

Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor

PDB ID 2q91

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