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2qcb

From Proteopedia

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_2qcb", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:2qcb.jpg|left|200px]]
 
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==T7-tagged full-length streptavidin complexed with ruthenium ligand==
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The line below this paragraph, containing "STRUCTURE_2qcb", creates the "Structure Box" on the page.
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<StructureSection load='2qcb' size='340' side='right'caption='[[2qcb]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qcb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QCB FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KYS:N-(4-{[(2-AMINOETHYL)AMINO]SULFONYL}PHENYL)-5-[(3AS,4S,6AR)-2-OXOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANAMIDE-(1,2,3,4,5,6-ETA)-BENZENE-CHLORO-RUTHENIUM(III)'>KYS</scene></td></tr>
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{{STRUCTURE_2qcb| PDB=2qcb | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qcb OCA], [https://pdbe.org/2qcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qcb RCSB], [https://www.ebi.ac.uk/pdbsum/2qcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qcb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qc/2qcb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qcb ConSurf].
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<div style="clear:both"></div>
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'''T7-tagged full-length streptavidin complexed with ruthenium ligand'''
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==See Also==
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*[[Avidin 3D structures|Avidin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2QCB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QCB OCA].
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[[Category: Large Structures]]
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==Reference==
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X-ray structure and designed evolution of an artificial transfer hydrogenase., Creus M, Pordea A, Rossel T, Sardo A, Letondor C, Ivanova A, Letrong I, Stenkamp RE, Ward TR, Angew Chem Int Ed Engl. 2008;47(8):1400-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18176932 18176932]
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[[Category: Single protein]]
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[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
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[[Category: Creus, M.]]
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[[Category: Creus M]]
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[[Category: Pordea, A.]]
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[[Category: Le Trong I]]
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[[Category: Stenkamp, R E.]]
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[[Category: Pordea A]]
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[[Category: Trong, I Le.]]
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[[Category: Stenkamp RE]]
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[[Category: Ward, T R.]]
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[[Category: Ward TR]]
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[[Category: Artificial transfer hydrogenase]]
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[[Category: Biotin binding protein]]
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[[Category: Streptavidin]]
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[[Category: T7-tag]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 30 13:17:17 2008''
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Current revision

T7-tagged full-length streptavidin complexed with ruthenium ligand

PDB ID 2qcb

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