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2qh7

From Proteopedia

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[[Image:2qh7.png|left|200px]]
 
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==MitoNEET is a uniquely folded 2Fe-2S outer mitochondrial membrane protein stabilized by pioglitazone==
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The line below this paragraph, containing "STRUCTURE_2qh7", creates the "Structure Box" on the page.
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<StructureSection load='2qh7' size='340' side='right'caption='[[2qh7]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qh7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QH7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
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{{STRUCTURE_2qh7| PDB=2qh7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qh7 OCA], [https://pdbe.org/2qh7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qh7 RCSB], [https://www.ebi.ac.uk/pdbsum/2qh7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qh7 ProSAT]</span></td></tr>
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</table>
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===MitoNEET is a uniquely folded 2Fe-2S outer mitochondrial membrane protein stabilized by pioglitazone===
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== Function ==
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[https://www.uniprot.org/uniprot/CISD1_HUMAN CISD1_HUMAN] Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions.<ref>PMID:17584744</ref> <ref>PMID:17766440</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_17766440}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17766440 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qh7_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17766440}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[2qh7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QH7 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qh7 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:017766440</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Axelrod, H L.]]
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[[Category: Large Structures]]
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[[Category: Capraro, D.]]
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[[Category: Abresch EC]]
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[[Category: Cohen, A E.]]
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[[Category: Axelrod HL]]
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[[Category: Dixon, J E.]]
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[[Category: Capraro D]]
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[[Category: E C., Abresch..]]
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[[Category: Cohen AE]]
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[[Category: Jennings, P A.]]
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[[Category: Dixon JE]]
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[[Category: Murphy, A N.]]
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[[Category: Jennings PA]]
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[[Category: Nechushtai, R.]]
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[[Category: Murphy AN]]
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[[Category: Paddock, M L.]]
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[[Category: Nechushtai R]]
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[[Category: Roy, M.]]
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[[Category: Paddock ML]]
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[[Category: Wiley, S E.]]
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[[Category: Roy M]]
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[[Category: 2fe-2s protein]]
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[[Category: Wiley SE]]
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[[Category: Metal binding protein]]
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[[Category: Mitoneet]]
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[[Category: Outer mitochrodrial membrane protein]]
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[[Category: Pioglitazone binding]]
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Current revision

MitoNEET is a uniquely folded 2Fe-2S outer mitochondrial membrane protein stabilized by pioglitazone

PDB ID 2qh7

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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