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2qwx

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{{Seed}}
 
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[[Image:2qwx.png|left|200px]]
 
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==Crystal Structure of Quinone Reductase II==
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The line below this paragraph, containing "STRUCTURE_2qwx", creates the "Structure Box" on the page.
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<StructureSection load='2qwx' size='340' side='right'caption='[[2qwx]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qwx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QWX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=ML1:N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE'>ML1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2qwx| PDB=2qwx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qwx OCA], [https://pdbe.org/2qwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qwx RCSB], [https://www.ebi.ac.uk/pdbsum/2qwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qwx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qw/2qwx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qwx ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Quinone Reductase II===
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==See Also==
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*[[Quinone reductase 3D structures|Quinone reductase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_18254726}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 18254726 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_18254726}}
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==About this Structure==
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2QWX is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QWX OCA].
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==Reference==
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<ref group="xtra">PMID:18254726</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Boutin, J A.]]
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[[Category: Large Structures]]
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[[Category: Calamini, B.]]
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[[Category: Boutin JA]]
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[[Category: Mesecar, A D.]]
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[[Category: Calamini B]]
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[[Category: Santarsiero, B D.]]
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[[Category: Mesecar AD]]
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[[Category: Cytoplasm]]
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[[Category: Santarsiero BD]]
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[[Category: Fad]]
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[[Category: Flavoprotein]]
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[[Category: Metal-binding]]
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[[Category: Oxidoreductase]]
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[[Category: Polymorphism]]
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[[Category: Qr2]]
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[[Category: Zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:58:37 2009''
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Current revision

Crystal Structure of Quinone Reductase II

PDB ID 2qwx

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