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2qzh

From Proteopedia

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{{Seed}}
 
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[[Image:2qzh.png|left|200px]]
 
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==SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF==
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The line below this paragraph, containing "STRUCTURE_2qzh", creates the "Structure Box" on the page.
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<SX load='2qzh' size='340' side='right' viewer='molstar' caption='[[2qzh]], [[Resolution|resolution]] 14.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qzh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QZH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qzh OCA], [https://pdbe.org/2qzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qzh RCSB], [https://www.ebi.ac.uk/pdbsum/2qzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qzh ProSAT]</span></td></tr>
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{{STRUCTURE_2qzh| PDB=2qzh | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/2qzh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qzh ConSurf].
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<div style="clear:both"></div>
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===SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF===
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==See Also==
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*[[CD55|CD55]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_17804498}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 17804498 is the PubMed ID number.
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</SX>
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-->
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{{ABSTRACT_PUBMED_17804498}}
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==About this Structure==
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2QZH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZH OCA].
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==Reference==
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<ref group="xtra">PMID:17804498</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bowman, V D.]]
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[[Category: Large Structures]]
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[[Category: Chipman, P R.]]
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[[Category: Bator Kelly CM]]
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[[Category: Hafenstein, S.]]
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[[Category: Bowman VD]]
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[[Category: Kelly, C M.Bator.]]
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[[Category: Chipman PR]]
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[[Category: Lin, F.]]
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[[Category: Hafenstein S]]
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[[Category: Medof, M E.]]
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[[Category: Lin F]]
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[[Category: Rossmann, M G.]]
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[[Category: Medof ME]]
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[[Category: Alternative splicing]]
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[[Category: Rossmann MG]]
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[[Category: Blood group antigen]]
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[[Category: Complement pathway]]
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[[Category: Glycoprotein]]
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[[Category: Gpi-anchor]]
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[[Category: Immune response]]
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[[Category: Immune system]]
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[[Category: Innate immunity]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Polymorphism]]
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[[Category: Scr2/3 of daf fitted into cryoem density of cvb3-rd complexed with daf]]
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[[Category: Sushi]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:00:55 2009''
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Current revision

SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF

2qzh, resolution 14.00Å

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OCA

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