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2r2y

From Proteopedia

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{{Seed}}
 
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[[Image:2r2y.png|left|200px]]
 
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==Crystal structure of the proteasomal Rpn13 PRU-domain==
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The line below this paragraph, containing "STRUCTURE_2r2y", creates the "Structure Box" on the page.
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<StructureSection load='2r2y' size='340' side='right'caption='[[2r2y]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2r2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R2Y FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r2y OCA], [https://pdbe.org/2r2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r2y RCSB], [https://www.ebi.ac.uk/pdbsum/2r2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r2y ProSAT]</span></td></tr>
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{{STRUCTURE_2r2y| PDB=2r2y | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the proteasomal Rpn13 PRU-domain===
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[https://www.uniprot.org/uniprot/ADRM1_MOUSE ADRM1_MOUSE] Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.<ref>PMID:15819879</ref> <ref>PMID:18497827</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_18497827}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18497827 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r2/2r2y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_18497827}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r2y ConSurf].
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2R2Y is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2Y OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:18497827</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Dikic, I.]]
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[[Category: Dikic I]]
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[[Category: Finley, D.]]
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[[Category: Finley D]]
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[[Category: Groll, M.]]
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[[Category: Groll M]]
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[[Category: Walters, K.]]
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[[Category: Walters K]]
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[[Category: 19s regulator]]
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[[Category: Ph-domain]]
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[[Category: Proteasome]]
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[[Category: Protein binding]]
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[[Category: Receptor]]
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[[Category: Receptor domain for ubiquitin and proteasome binding]]
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[[Category: Ubiquitin]]
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[[Category: Ubiquitin-proteasome-degradation pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:48:09 2009''
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Current revision

Crystal structure of the proteasomal Rpn13 PRU-domain

PDB ID 2r2y

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