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2rhc

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[[Image:2rhc.png|left|200px]]
 
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{{STRUCTURE_2rhc| PDB=2rhc | SCENE= }}
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==Actinorhodin ketordeuctase, actKR, with NADP+ and Inhibitor Emodin==
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<StructureSection load='2rhc' size='340' side='right'caption='[[2rhc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===Actinorhodin ketordeuctase, actKR, with NADP+ and Inhibitor Emodin===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2rhc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RHC FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18205400}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EMO:3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE'>EMO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rhc OCA], [https://pdbe.org/2rhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rhc RCSB], [https://www.ebi.ac.uk/pdbsum/2rhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rhc ProSAT]</span></td></tr>
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[[2rhc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHC OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/ACT3_STRCO ACT3_STRCO]
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<ref group="xtra">PMID:018205400</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/2rhc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rhc ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
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[[Category: Korman, T P.]]
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[[Category: Korman TP]]
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[[Category: Tsai, S C.]]
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[[Category: Tsai S-C]]
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[[Category: Actinorhodin]]
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[[Category: Combinatorial biosynthesis]]
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[[Category: Ketoreductase]]
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[[Category: Oxidoreductase]]
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[[Category: Polyketide]]
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[[Category: Short chain dehydrogenase/reductase]]
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Current revision

Actinorhodin ketordeuctase, actKR, with NADP+ and Inhibitor Emodin

PDB ID 2rhc

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