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3c3n

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_3c3n", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:3c3n.png|left|200px]]
 
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==Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y==
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The line below this paragraph, containing "STRUCTURE_3c3n", creates the "Structure Box" on the page.
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<StructureSection load='3c3n' size='340' side='right'caption='[[3c3n]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3c3n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C3N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C3N FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3c3n| PDB=3c3n | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c3n OCA], [https://pdbe.org/3c3n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c3n RCSB], [https://www.ebi.ac.uk/pdbsum/3c3n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c3n ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c3/3c3n_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c3n ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y===
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==See Also==
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*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18302934}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 18302934 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18302934}}
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==About this Structure==
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[[3c3n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C3N OCA].
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==Reference==
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<ref group="xtra">PMID:018302934</ref><references group="xtra"/>
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[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
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[[Category: Iulek, J.]]
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[[Category: Iulek J]]
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[[Category: Nonato, M C.]]
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[[Category: Nonato MC]]
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[[Category: Pinheiro, M P.]]
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[[Category: Pinheiro MP]]
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[[Category: Dhodh]]
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[[Category: Dihydroorotate dehydrogenase]]
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[[Category: Oxidoreductase]]
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[[Category: Pyrd]]
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[[Category: Trypanosoma cruzi strain y]]
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Current revision

Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y

PDB ID 3c3n

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