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3cky

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[[Image:3cky.png|left|200px]]
 
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{{STRUCTURE_3cky| PDB=3cky | SCENE= }}
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==Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation==
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<StructureSection load='3cky' size='340' side='right'caption='[[3cky]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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===Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3cky]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Eubacterium_barkeri Eubacterium barkeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CKY FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18680749}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cky OCA], [https://pdbe.org/3cky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cky RCSB], [https://www.ebi.ac.uk/pdbsum/3cky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cky ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3cky]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Eubacterium_barkeri Eubacterium barkeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKY OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/HMGD_EUBBA HMGD_EUBBA] Catalyzes the conversion of 2-formylglutarate to (S)-2-hydroxymethylglutarate. Has very low activity with (S)-3-hydroxyisobutyrate.<ref>PMID:18680749</ref>
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:018680749</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: 2-hydroxymethylglutarate dehydrogenase]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/3cky_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cky ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Eubacterium barkeri]]
[[Category: Eubacterium barkeri]]
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[[Category: Alhapel, A.]]
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[[Category: Large Structures]]
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[[Category: Essen, L O.]]
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[[Category: Alhapel A]]
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[[Category: Pierik, A J.]]
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[[Category: Essen L-O]]
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[[Category: Reitz, S.]]
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[[Category: Pierik AJ]]
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[[Category: Oxidoreductase]]
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[[Category: Reitz S]]
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[[Category: Rossmann fold]]
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[[Category: Two domain enzyme]]
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Current revision

Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation

PDB ID 3cky

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