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3cw3

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{{Seed}}
 
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[[Image:3cw3.png|left|200px]]
 
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==Crystal structure of AIM1g1==
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The line below this paragraph, containing "STRUCTURE_3cw3", creates the "Structure Box" on the page.
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<StructureSection load='3cw3' size='340' side='right'caption='[[3cw3]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3cw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CW3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_3cw3| PDB=3cw3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cw3 OCA], [https://pdbe.org/3cw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3cw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cw3 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of AIM1g1===
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== Function ==
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[https://www.uniprot.org/uniprot/CRBG1_HUMAN CRBG1_HUMAN] May function as suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_18582473}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 18582473 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cw/3cw3_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_18582473}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Disease==
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</jmolCheckbox>
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Known disease associated with this structure: Oculocutaneous albinism, type IV OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606202 606202]], Skin/hair/eye pigmentation 5, black/nonblack hair OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606202 606202]], Skin/hair/eye pigmentation 5, dark/fair skin OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606202 606202]], Skin/hair/eye pigmentation 5, dark/light eyes OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606202 606202]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cw3 ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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__TOC__
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3CW3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW3 OCA].
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</StructureSection>
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==Reference==
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Exploring the limits of sequence and structure in a variant betagamma-crystallin domain of the protein absent in melanoma-1 (AIM1)., Aravind P, Wistow G, Sharma Y, Sankaranarayanan R, J Mol Biol. 2008 Sep 5;381(3):509-18. Epub 2008 Jun 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18582473 18582473]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Aravind, P.]]
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[[Category: Aravind P]]
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[[Category: Sankaranarayanan, R.]]
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[[Category: Sankaranarayanan R]]
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[[Category: Sharma, Y.]]
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[[Category: Sharma Y]]
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[[Category: Beta gamma-crystallin]]
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[[Category: Greek key]]
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[[Category: Lectin]]
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[[Category: Oncoprotein]]
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[[Category: Tryptophan corner]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 13 13:38:47 2008''
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Current revision

Crystal structure of AIM1g1

PDB ID 3cw3

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OCA

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