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3dba

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{{Seed}}
 
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[[Image:3dba.png|left|200px]]
 
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==Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C==
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The line below this paragraph, containing "STRUCTURE_3dba", creates the "Structure Box" on the page.
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<StructureSection load='3dba' size='340' side='right'caption='[[3dba]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3dba]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DBA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=35G:GUANOSINE-3,5-MONOPHOSPHATE'>35G</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_3dba| PDB=3dba | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dba OCA], [https://pdbe.org/3dba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dba RCSB], [https://www.ebi.ac.uk/pdbsum/3dba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dba ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PDE6C_CHICK PDE6C_CHICK]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/db/3dba_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dba ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C===
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==See Also==
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*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18614542}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 18614542 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18614542}}
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==About this Structure==
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3DBA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBA OCA].
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==Reference==
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The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change., Martinez SE, Heikaus CC, Klevit RE, Beavo JA, J Biol Chem. 2008 Sep 19;283(38):25913-9. Epub 2008 Jul 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18614542 18614542]
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[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Beavo, J A.]]
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[[Category: Beavo JA]]
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[[Category: Heikaus, C C.]]
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[[Category: Heikaus CC]]
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[[Category: Klevit, R E.]]
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[[Category: Klevit RE]]
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[[Category: Martinez, S E.]]
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[[Category: Martinez SE]]
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[[Category: 3s']]
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[[Category: 5' cgmp]]
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[[Category: Cgmp]]
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[[Category: Cyclic nucleotide phosphodiesterase]]
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[[Category: Gaf domain]]
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[[Category: Hydrolase]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Prenylation]]
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[[Category: Sensory transduction]]
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[[Category: Vision]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 24 09:17:41 2008''
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Current revision

Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C

PDB ID 3dba

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