This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3e1s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:44, 21 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3e1s.png|left|200px]]
 
-
<!--
+
==Structure of an N-terminal truncation of Deinococcus radiodurans RecD2==
-
The line below this paragraph, containing "STRUCTURE_3e1s", creates the "Structure Box" on the page.
+
<StructureSection load='3e1s' size='340' side='right'caption='[[3e1s]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3e1s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E1S FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e1s OCA], [https://pdbe.org/3e1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e1s RCSB], [https://www.ebi.ac.uk/pdbsum/3e1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e1s ProSAT]</span></td></tr>
-
{{STRUCTURE_3e1s| PDB=3e1s | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RECDL_DEIRA RECDL_DEIRA] DNA-dependent ATPase (ssDNA better than dsDNA) and ATP-dependent 5'-3' DNA helicase. Appears to move along DNA in single base steps, powered by hydrolysis of 1 molecule of ATP. Has low processivity; short (20 bp) substrates with 5'-overhangs or forked ends are the best substrates, is much less efficient on 52 or 76 bp substrates with 5'- overhangs. The presence of single-stranded DNA-binding protein (SSB) increases unwinding 4-5 fold. Has no activity on blunt DNA or DNA with 3'-overhangs. Requires at least 10 bases of 5'-ssDNA for helicase activity.<ref>PMID:15466873</ref> <ref>PMID:19490894</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e1/3e1s_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e1s ConSurf].
 +
<div style="clear:both"></div>
-
===Structure of an N-terminal truncation of Deinococcus radiodurans RecD2===
+
==See Also==
-
 
+
*[[Exonuclease 3D structures|Exonuclease 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_18668125}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 18668125 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_18668125}}
+
-
 
+
-
==About this Structure==
+
-
3E1S is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E1S OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:18668125</ref><references group="xtra"/>
+
[[Category: Deinococcus radiodurans]]
[[Category: Deinococcus radiodurans]]
-
[[Category: Cook, N.]]
+
[[Category: Large Structures]]
-
[[Category: Court, R.]]
+
[[Category: Cook N]]
-
[[Category: Griffiths, S P.]]
+
[[Category: Court R]]
-
[[Category: Saikrishnan, K.]]
+
[[Category: Griffiths SP]]
-
[[Category: Wigley, D B.]]
+
[[Category: Saikrishnan K]]
-
[[Category: Alpha and beta protein]]
+
[[Category: Wigley DB]]
-
[[Category: Atp-binding]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Nucleotide-binding]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:04:45 2009''
+

Current revision

Structure of an N-terminal truncation of Deinococcus radiodurans RecD2

PDB ID 3e1s

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3e1s"
Personal tools