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3el6

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[[Image:3el6.png|left|200px]]
 
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{{STRUCTURE_3el6| PDB=3el6 | SCENE= }}
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==Crystal Structure of the Erythromycin Dehydratase==
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<StructureSection load='3el6' size='340' side='right'caption='[[3el6]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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===Crystal Structure of the Erythromycin Dehydratase===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3el6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EL6 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_18952099}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3el6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3el6 OCA], [https://pdbe.org/3el6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3el6 RCSB], [https://www.ebi.ac.uk/pdbsum/3el6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3el6 ProSAT]</span></td></tr>
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[[3el6]] is a 1 chain structure of [[6-deoxyerythronolide B synthase (DEBS)]] with sequence from [http://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EL6 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ERYA2_SACER ERYA2_SACER]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/3el6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3el6 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[6-deoxyerythronolide B synthase (DEBS)|6-deoxyerythronolide B synthase (DEBS)]]
*[[6-deoxyerythronolide B synthase (DEBS)|6-deoxyerythronolide B synthase (DEBS)]]
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*[[6-deoxyerythronolide B synthase 3D structures|6-deoxyerythronolide B synthase 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:018952099</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharopolyspora erythraea]]
[[Category: Saccharopolyspora erythraea]]
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[[Category: Keatinge-Clay, A T.]]
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[[Category: Keatinge-Clay AT]]
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[[Category: Acyltransferase]]
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[[Category: Antibiotic biosynthesis]]
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[[Category: Dehydratase double hotdog fold cis-proline]]
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[[Category: Lyase]]
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[[Category: Multifunctional enzyme]]
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[[Category: Nadp]]
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[[Category: Phosphopantetheine]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of the Erythromycin Dehydratase

PDB ID 3el6

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