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3fi8

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==Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020==
==Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020==
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<StructureSection load='3fi8' size='340' side='right' caption='[[3fi8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3fi8' size='340' side='right'caption='[[3fi8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3fi8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FI8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3fi8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FI8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OPE:PHOSPHORIC+ACID+MONO-(2-AMINO-ETHYL)+ESTER'>OPE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF14_0020 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OPE:PHOSPHORIC+ACID+MONO-(2-AMINO-ETHYL)+ESTER'>OPE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fi8 OCA], [http://pdbe.org/3fi8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fi8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fi8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fi8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fi8 OCA], [https://pdbe.org/3fi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fi8 RCSB], [https://www.ebi.ac.uk/pdbsum/3fi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fi8 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8IM71_PLAF7 Q8IM71_PLAF7]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fi/3fi8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fi/3fi8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fi8 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fi8 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Choline kinase 3D structures|Choline kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Plaf7]]
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[[Category: Large Structures]]
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[[Category: Amaya, M F]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Arrowsmith, C H]]
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[[Category: Amaya MF]]
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[[Category: Artz, J D]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev, A]]
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[[Category: Artz JD]]
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[[Category: Bountra, C]]
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[[Category: Bochkarev A]]
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[[Category: Cossar, D]]
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[[Category: Bountra C]]
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[[Category: Edwards, A M]]
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[[Category: Cossar D]]
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[[Category: Hills, T]]
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[[Category: Edwards AM]]
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[[Category: Hui, R]]
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[[Category: Hills T]]
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[[Category: Kozieradzki, I]]
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[[Category: Hui R]]
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[[Category: Lew, J]]
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[[Category: Kozieradzki I]]
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[[Category: Pizarro, J C]]
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[[Category: Lew J]]
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[[Category: Structural genomic]]
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[[Category: Pizarro JC]]
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[[Category: Schapira, M]]
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[[Category: Schapira M]]
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[[Category: Senesterra, G]]
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[[Category: Senesterra G]]
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[[Category: Vedadi, M]]
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[[Category: Vedadi M]]
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[[Category: Wasney, G]]
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[[Category: Wasney G]]
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[[Category: Weigelt, J]]
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[[Category: Weigelt J]]
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[[Category: Wernimont, A K]]
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[[Category: Wernimont AK]]
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[[Category: Xiao, T]]
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[[Category: Xiao T]]
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[[Category: Choline kinase]]
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[[Category: Kinase]]
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[[Category: Malaria]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020

PDB ID 3fi8

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