3g1m
From Proteopedia
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- | [[Image:3g1m.png|left|200px]] | ||
- | < | + | ==EthR from Mycobacterium tuberculosis in complex with compound BDM31381== |
- | + | <StructureSection load='3g1m' size='340' side='right'caption='[[3g1m]], [[Resolution|resolution]] 1.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3g1m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G1M FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RF3:1-(THIOPHEN-2-YLACETYL)-4-(3-THIOPHEN-2-YL-1,2,4-OXADIAZOL-5-YL)PIPERIDINE'>RF3</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1m OCA], [https://pdbe.org/3g1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g1m RCSB], [https://www.ebi.ac.uk/pdbsum/3g1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1m ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1m_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g1m ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |
- | + | == References == | |
- | + | <references/> | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Large Structures]] | |
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- | [[ | + | |
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- | == | + | |
- | < | + | |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
- | [[Category: Aumercier | + | [[Category: Aumercier M]] |
- | [[Category: Baulard | + | [[Category: Baulard AR]] |
- | [[Category: Bifani | + | [[Category: Bifani P]] |
- | [[Category: Carette | + | [[Category: Carette X]] |
- | [[Category: Delcroix | + | [[Category: Delcroix G]] |
- | [[Category: Deprez | + | [[Category: Deprez B]] |
- | [[Category: Deprez-Poulain | + | [[Category: Deprez-Poulain R]] |
- | [[Category: Desroses | + | [[Category: Desroses M]] |
- | [[Category: Dirie | + | [[Category: Dirie B]] |
- | [[Category: Frenois | + | [[Category: Frenois F]] |
- | [[Category: Leroux | + | [[Category: Leroux F]] |
- | [[Category: Locht | + | [[Category: Locht C]] |
- | [[Category: Mathys | + | [[Category: Mathys V]] |
- | [[Category: Singhal | + | [[Category: Singhal A]] |
- | [[Category: Villeret | + | [[Category: Villeret V]] |
- | [[Category: Willand | + | [[Category: Willand N]] |
- | [[Category: Willery | + | [[Category: Willery E]] |
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Current revision
EthR from Mycobacterium tuberculosis in complex with compound BDM31381
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Categories: Large Structures | Mycobacterium tuberculosis | Aumercier M | Baulard AR | Bifani P | Carette X | Delcroix G | Deprez B | Deprez-Poulain R | Desroses M | Dirie B | Frenois F | Leroux F | Locht C | Mathys V | Singhal A | Villeret V | Willand N | Willery E