3g1z
From Proteopedia
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| - | [[Image:3g1z.png|left|200px]] | ||
| - | + | ==Structure of IDP01693/yjeA, a potential t-RNA synthetase from Salmonella typhimurium== | |
| - | + | <StructureSection load='3g1z' size='340' side='right'caption='[[3g1z]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3g1z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G1Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1z OCA], [https://pdbe.org/3g1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g1z RCSB], [https://www.ebi.ac.uk/pdbsum/3g1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1z ProSAT], [https://www.topsan.org/Proteins/CSGID/3g1z TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/EPMA_SALTY EPMA_SALTY] With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34' (Probable). Can also use L-alpha-lysine as a substrate, but probably with lower efficiency. Cannot aminoacylate tRNA(Lys) with lysine.[HAMAP-Rule:MF_00174]<ref>PMID:20670890</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1z_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | == | + | </jmolCheckbox> |
| - | [[3g1z]] is a 2 chain structure with sequence from [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g1z ConSurf]. |
| - | + | <div style="clear:both"></div> | |
| - | + | == References == | |
| - | < | + | <references/> |
| - | [[ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
| - | [ | + | [[Category: Large Structures]] |
| - | [ | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| - | [ | + | [[Category: Anderson WF]] |
| - | [ | + | [[Category: Cuff ME]] |
| - | [ | + | [[Category: Edwards AM]] |
| - | [ | + | [[Category: Evdokimova E]] |
| - | [ | + | [[Category: Kudritska M]] |
| - | [[ | + | [[Category: Savchenko A]] |
| - | [ | + | [[Category: Singer AU]] |
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Current revision
Structure of IDP01693/yjeA, a potential t-RNA synthetase from Salmonella typhimurium
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