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3gvj

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{{Seed}}
 
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[[Image:3gvj.jpg|left|200px]]
 
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<!--
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==Crystal structure of an endo-neuraminidaseNF mutant==
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The line below this paragraph, containing "STRUCTURE_3gvj", creates the "Structure Box" on the page.
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<StructureSection load='3gvj' size='340' side='right'caption='[[3gvj]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3gvj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_K1F Escherichia phage K1F]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GVJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene>, <scene name='pdbligand=SLB:5-N-ACETYL-BETA-D-NEURAMINIC+ACID'>SLB</scene></td></tr>
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{{STRUCTURE_3gvj| PDB=3gvj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gvj OCA], [https://pdbe.org/3gvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gvj RCSB], [https://www.ebi.ac.uk/pdbsum/3gvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gvj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FIBER_BPK1F FIBER_BPK1F] Responsible for initial absorption of the phage to the host bacterium. Degrades the alpha-2,8-linked polysialic acid K1 capsule by cleaving within the polymer chain of polysialic acid.<ref>PMID:20096705</ref> <ref>PMID:3546309</ref> The C-terminal chaperone protein mediates homotrimerization and proper folding of the catalytic endo-N trimer.<ref>PMID:12556457</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/3gvj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gvj ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of an endo-neuraminidaseNF mutant===
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==See Also==
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
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*[[Tailspike protein 3D structures|Tailspike protein 3D structures]]
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== References ==
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The line below this paragraph, {{ABSTRACT_PUBMED_20096705}}, adds the Publication Abstract to the page
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 20096705 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_20096705}}
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[[Category: Escherichia phage K1F]]
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[[Category: Large Structures]]
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==About this Structure==
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[[Category: Dickmanns A]]
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3GVJ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_k1f Enterobacteria phage k1f]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GVJ OCA].
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[[Category: Ficner R]]
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[[Category: Schulz EC]]
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==Reference==
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<ref group="xtra">PMID:20096705</ref><references group="xtra"/>
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[[Category: Endo-alpha-sialidase]]
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[[Category: Enterobacteria phage k1f]]
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[[Category: Dickmanns, A.]]
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[[Category: Ficner, R.]]
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[[Category: Schulz, E C.]]
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[[Category: Endo-neuraminidase]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Polysialic acid]]
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[[Category: Triple-beta helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:21:31 2010''
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Current revision

Crystal structure of an endo-neuraminidaseNF mutant

PDB ID 3gvj

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