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3hm7

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==Crystal structure of allantoinase from Bacillus halodurans C-125==
==Crystal structure of allantoinase from Bacillus halodurans C-125==
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<StructureSection load='3hm7' size='340' side='right' caption='[[3hm7]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='3hm7' size='340' side='right'caption='[[3hm7]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hm7]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HM7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HM7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hm7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HM7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">allB, pucH, BH2309 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=86665 Bacillus halodurans])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Allantoinase Allantoinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.5 3.5.2.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hm7 OCA], [https://pdbe.org/3hm7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hm7 RCSB], [https://www.ebi.ac.uk/pdbsum/3hm7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hm7 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3hm7 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hm7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hm7 RCSB], [http://www.ebi.ac.uk/pdbsum/3hm7 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3hm7 TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ALLB_HALH5 ALLB_HALH5] Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.[HAMAP-Rule:MF_01645]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hm/3hm7_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hm/3hm7_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hm7 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Allantoinase]]
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[[Category: Alkalihalobacillus halodurans]]
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[[Category: Bacillus halodurans]]
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[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Miller, S]]
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[[Category: Miller S]]
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[[Category: Structural genomic]]
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[[Category: Patskovsky Y]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: Raushel FM]]
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[[Category: Patskovsky, Y]]
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[[Category: Romero R]]
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[[Category: Raushel, F M]]
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[[Category: Rutter M]]
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[[Category: Romero, R]]
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[[Category: Sauder JM]]
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[[Category: Rutter, M]]
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[[Category: Wasserman SR]]
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[[Category: Sauder, J M]]
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[[Category: Wasserman, S R]]
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[[Category: Dna-binding]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Metallo-dependent hydrolase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Purine metabolism]]
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Current revision

Crystal structure of allantoinase from Bacillus halodurans C-125

PDB ID 3hm7

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