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3hnc

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[[Image:3hnc.png|left|200px]]
 
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{{STRUCTURE_3hnc| PDB=3hnc | SCENE= }}
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==Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP==
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<StructureSection load='3hnc' size='340' side='right'caption='[[3hnc]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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===Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3hnc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HNC FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21336276}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hnc OCA], [https://pdbe.org/3hnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hnc RCSB], [https://www.ebi.ac.uk/pdbsum/3hnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hnc ProSAT]</span></td></tr>
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[[3hnc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HNC OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RIR1_HUMAN RIR1_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
==See Also==
==See Also==
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*[[Ribonucleotide reductase|Ribonucleotide reductase]]
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*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021336276</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Large Structures]]
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[[Category: Dealwis, C G.]]
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[[Category: Dealwis CG]]
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[[Category: Fairman, J W.]]
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[[Category: Fairman JW]]
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[[Category: Wijerathna, S R.]]
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[[Category: Wijerathna SR]]
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[[Category: Xu, H.]]
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[[Category: Xu H]]
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[[Category: Allosteric enzyme]]
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[[Category: Atp-binding]]
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[[Category: Dna replication]]
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[[Category: Nucleotide-binding]]
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[[Category: Oxidoreductase]]
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[[Category: Ribonucleotide reductase]]
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Current revision

Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP

PDB ID 3hnc

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