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3hst

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[[Image:3hst.png|left|200px]]
 
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{{STRUCTURE_3hst| PDB=3hst | SCENE= }}
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==N-Terminal RNASE H domain of rv2228c from mycobacterium tuberculosis as a fusion protein with maltose binding protein==
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<StructureSection load='3hst' size='340' side='right'caption='[[3hst]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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===N-Terminal RNASE H domain of rv2228c from mycobacterium tuberculosis as a fusion protein with maltose binding protein===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3hst]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HST FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20363939}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900009:alpha-maltotriose'>PRD_900009</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hst OCA], [https://pdbe.org/3hst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hst RCSB], [https://www.ebi.ac.uk/pdbsum/3hst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hst ProSAT]</span></td></tr>
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[[3hst]] is a 4 chain structure of [[Maltose-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HST OCA].
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</table>
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== Function ==
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==See Also==
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[https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.
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*[[Maltose-binding protein|Maltose-binding protein]]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==Reference==
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Check<jmol>
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<ref group="xtra">PMID:020363939</ref><references group="xtra"/>
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<jmolCheckbox>
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[[Category: Escherichia coli k-12]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hs/3hst_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hst ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Baker, E N.]]
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[[Category: Baker EN]]
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[[Category: Watkins, H A.]]
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[[Category: Watkins HA]]
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[[Category: Fusion protein]]
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[[Category: Hydrolase]]
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[[Category: Maltose binding protein]]
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[[Category: Mycobacterium]]
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[[Category: Ribonuclease h1]]
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[[Category: Rv2228c n-terminal domain]]
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[[Category: Tuberculosis]]
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Current revision

N-Terminal RNASE H domain of rv2228c from mycobacterium tuberculosis as a fusion protein with maltose binding protein

PDB ID 3hst

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