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3i0o

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[[Image:3i0o.png|left|200px]]
 
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{{STRUCTURE_3i0o| PDB=3i0o | SCENE= }}
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==Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, in complex with ADP and Spectinomcyin==
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<StructureSection load='3i0o' size='340' side='right'caption='[[3i0o]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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===Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, in complex with ADP and Spectinomcyin===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3i0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila_serogroup_1 Legionella pneumophila serogroup 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I0O FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20089863}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SMI:SPECTINOMYCIN'>SMI</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i0o OCA], [https://pdbe.org/3i0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i0o RCSB], [https://www.ebi.ac.uk/pdbsum/3i0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i0o ProSAT]</span></td></tr>
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[[3i0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_serogroup_1 Legionella pneumophila serogroup 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I0O OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O06916_LEGPN O06916_LEGPN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i0/3i0o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i0o ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phosphotransferase|Phosphotransferase]]
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*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020089863</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Legionella pneumophila serogroup 1]]
[[Category: Legionella pneumophila serogroup 1]]
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[[Category: Berghuis, A M.]]
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[[Category: Berghuis AM]]
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[[Category: Fong, D H.]]
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[[Category: Fong DH]]
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[[Category: Hwang, J.]]
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[[Category: Hwang J]]
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[[Category: Lemke, C T.]]
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[[Category: Lemke CT]]
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[[Category: Xiong, B.]]
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[[Category: Xiong B]]
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[[Category: Aminoglycoside phosphotransferase]]
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[[Category: Antibiotic resistance]]
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[[Category: Protein kinase]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, in complex with ADP and Spectinomcyin

PDB ID 3i0o

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