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3iec

From Proteopedia

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{{Seed}}
 
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[[Image:3iec.png|left|200px]]
 
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==Helicobacter pylori CagA Inhibits PAR1/MARK Family Kinases by Mimicking Host Substrates==
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The line below this paragraph, containing "STRUCTURE_3iec", creates the "Structure Box" on the page.
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<StructureSection load='3iec' size='340' side='right'caption='[[3iec]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3iec]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IEC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iec OCA], [https://pdbe.org/3iec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iec RCSB], [https://www.ebi.ac.uk/pdbsum/3iec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iec ProSAT]</span></td></tr>
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{{STRUCTURE_3iec| PDB=3iec | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MARK2_HUMAN MARK2_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3iec_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iec ConSurf].
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<div style="clear:both"></div>
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===Helicobacter pylori CagA Inhibits PAR1/MARK Family Kinases by Mimicking Host Substrates===
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==See Also==
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*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_19966800}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 19966800 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19966800}}
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==About this Structure==
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3IEC is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IEC OCA].
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==Reference==
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<ref group="xtra">PMID:19966800</ref><references group="xtra"/>
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[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Large Structures]]
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[[Category: Miller, M.]]
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[[Category: Miller M]]
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[[Category: Nesic, D.]]
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[[Category: Nesic D]]
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[[Category: Stebbins, C E.]]
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[[Category: Stebbins CE]]
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[[Category: Alternative promoter usage]]
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[[Category: Alternative splicing]]
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[[Category: Atp-binding]]
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[[Category: Cell membrane]]
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[[Category: Developmental protein]]
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[[Category: Differentiation]]
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[[Category: Kinase]]
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[[Category: Magnesium]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Protein-protein complex]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Signaling protein/toxin complex]]
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[[Category: Transferase]]
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[[Category: Virulence factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 16:42:50 2010''
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Current revision

Helicobacter pylori CagA Inhibits PAR1/MARK Family Kinases by Mimicking Host Substrates

PDB ID 3iec

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