3iys

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[[Image:3iys.png|left|200px]]
 
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==Homology model of avian polyomavirus asymmetric unit==
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The line below this paragraph, containing "STRUCTURE_3iys", creates the "Structure Box" on the page.
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<SX load='3iys' size='340' side='right' viewer='molstar' caption='[[3iys]], [[Resolution|resolution]] 11.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3iys]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Aves_polyomavirus_1 Aves polyomavirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iys FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iys OCA], [https://pdbe.org/3iys PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iys RCSB], [https://www.ebi.ac.uk/pdbsum/3iys PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iys ProSAT]</span></td></tr>
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{{STRUCTURE_3iys| PDB=3iys | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VP1_BFPYV VP1_BFPYV] Forms an icosahedral capsid with a T=7 symmetry and a 46-48 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with sialic acids on the cell surface to provide virion attachment to target cell. Once attached, the virion is internalized by endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating. Next, the virion uses the endoplasmic reticulum-associated degradation machinery to probably translocate in the cytosol before reaching the nucleus. Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2/Vp3 nuclear localization signal. In late phase of infection, neo-synthesized VP1 encapsulates replicated genomic DNA in the nucleus, and participates in rearranging nucleosomes around the viral DNA (By similarity).
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===Homology model of avian polyomavirus asymmetric unit===
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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</SX>
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The line below this paragraph, {{ABSTRACT_PUBMED_21239031}}, adds the Publication Abstract to the page
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[[Category: Aves polyomavirus 1]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21239031 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Atwood WJ]]
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{{ABSTRACT_PUBMED_21239031}}
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[[Category: Baker TS]]
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[[Category: Belnap DM]]
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==About this Structure==
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[[Category: Carter WS]]
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[[3iys]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Budgerigar_fledgling_disease_polyomavirus Budgerigar fledgling disease polyomavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYS OCA].
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[[Category: Cheng RH]]
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[[Category: Enderlein D]]
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==Reference==
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[[Category: Johne R]]
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<ref group="xtra">PMID:21239031</ref><references group="xtra"/>
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[[Category: Kawano M]]
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[[Category: Budgerigar fledgling disease polyomavirus]]
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[[Category: Nelson CDS]]
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[[Category: Atwood, W J.]]
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[[Category: Olson NH]]
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[[Category: Baker, T S.]]
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[[Category: Shen PS]]
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[[Category: Belnap, D M.]]
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[[Category: Swenson RD]]
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[[Category: Carter, W S.]]
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[[Category: Xing L]]
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[[Category: Cheng, R H.]]
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[[Category: Enderlein, D.]]
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[[Category: Johne, R.]]
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[[Category: Kawano, M.]]
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[[Category: Nelson, C D.S.]]
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[[Category: Olson, N H.]]
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[[Category: Shen, P S.]]
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[[Category: Swenson, R D.]]
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[[Category: Xing, L.]]
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Current revision

Homology model of avian polyomavirus asymmetric unit

3iys, resolution 11.30Å

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