This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3j4t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: '''Unreleased structure''' The entry 3j4t is ON HOLD Authors: Agard, D.A., Montabana, E.A. Description: Helical model of TubZ-Bt two-stranded filament)
Current revision (10:10, 21 February 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 3j4t is ON HOLD
+
==Helical model of TubZ-Bt two-stranded filament==
-
 
+
<SX load='3j4t' size='340' side='right' viewer='molstar' caption='[[3j4t]], [[Resolution|resolution]] 10.80&Aring;' scene=''>
-
Authors: Agard, D.A., Montabana, E.A.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3j4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis_serovar_israelensis Bacillus thuringiensis serovar israelensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J4T FirstGlance]. <br>
-
Description: Helical model of TubZ-Bt two-stranded filament
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.8&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j4t OCA], [https://pdbe.org/3j4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j4t RCSB], [https://www.ebi.ac.uk/pdbsum/3j4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j4t ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TUBZ_BACTI TUBZ_BACTI] A tubulin-like, filament forming GTPase; the motor component of the type III plasmid partition system which ensures correct segregation of the pBtoxis plasmid. Filaments may seed from the centromere-like site (tubC) when bound by DNA-binding protein TubR; the tubC-TubR complex stabilizes the TubZ filament. Filaments grow at the plus end and depolymerize at the minus end, a process called treadmilling. TubR-tubC complexes track the depolymerizing minus end of the filament, probably pulling plasmid within the cell (PubMed:20534443, PubMed:23010931, PubMed:25825718). Required for pBtoxis plasmid replication/partition (PubMed:16936050, PubMed:17873046). Binds the TubR-tubC complex; GTP is not required for binding to TubR-tubC. TubZ alone does not bind DNA (PubMed:17873046, PubMed:20534443, PubMed:25825718). Has a high GTPase activity in the presence of Mg(2+); in the presence of GTP assembles into dynamic filaments which upon polymerization bind almost exclusively GDP. Filament formation is cooperative, requiring a critical concentration. Formation occurs very quickly and is followed by disassembly as GTP is consumed (PubMed:18198178).<ref>PMID:16936050</ref> <ref>PMID:17873046</ref> <ref>PMID:18198178</ref> <ref>PMID:20534443</ref> <ref>PMID:23010931</ref> <ref>PMID:25825718</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</SX>
 +
[[Category: Bacillus thuringiensis serovar israelensis]]
 +
[[Category: Large Structures]]
 +
[[Category: Agard DA]]
 +
[[Category: Montabana EA]]

Current revision

Helical model of TubZ-Bt two-stranded filament

3j4t, resolution 10.80Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3j4t"
Personal tools