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3jre

From Proteopedia

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{{STRUCTURE_3jre| PDB=3jre | SCENE= }}
 
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===Crystal structure of Fis bound to 27 bp DNA F26 containing A-tract at center===
 
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{{ABSTRACT_PUBMED_20395367}}
 
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==Function==
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==Crystal structure of Fis bound to 27 bp DNA F26 containing A-tract at center==
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[[http://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI]] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref><ref>PMID:8836178</ref>
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<StructureSection load='3jre' size='340' side='right'caption='[[3jre]], [[Resolution|resolution]] 3.17&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3jre]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JRE FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.17&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jre OCA], [https://pdbe.org/3jre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jre RCSB], [https://www.ebi.ac.uk/pdbsum/3jre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jre ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref> <ref>PMID:8836178</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/3jre_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jre ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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[[3jre]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JRE OCA].
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*[[FIS protein|FIS protein]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:020395367</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: Escherichia coli]]
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</StructureSection>
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[[Category: Cascio, D.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Johnson, R C.]]
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[[Category: Large Structures]]
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[[Category: Stella, S.]]
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[[Category: Cascio D]]
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[[Category: Activator]]
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[[Category: Johnson RC]]
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[[Category: Dna bending]]
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[[Category: Stella S]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Dna-binding]]
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[[Category: Hth domain]]
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[[Category: Indirect recognition]]
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[[Category: Minor groove compression]]
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[[Category: Protein-dna complex]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Current revision

Crystal structure of Fis bound to 27 bp DNA F26 containing A-tract at center

PDB ID 3jre

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