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3jum

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==Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in complex with 5-bromo-2-((1S,3R)-3-carboxycyclohexylamino)benzoic acid==
==Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in complex with 5-bromo-2-((1S,3R)-3-carboxycyclohexylamino)benzoic acid==
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<StructureSection load='3jum' size='340' side='right' caption='[[3jum]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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<StructureSection load='3jum' size='340' side='right'caption='[[3jum]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3jum]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_sp. Burkholderia sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JUM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3jum]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_lata Burkholderia lata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JUM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AOD:5-BROMO-2-{[(1S,3R)-3-CARBOXYCYCLOHEXYL]AMINO}BENZOIC+ACID'>AOD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jun|3jun]], [[3juo|3juo]], [[3jup|3jup]], [[3juq|3juq]], [[3bo4|3bo4]], [[3cnm|3cnm]], [[3dzl|3dzl]], [[3b4p|3b4p]], [[3ex9|3ex9]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AOD:5-BROMO-2-{[(1S,3R)-3-CARBOXYCYCLOHEXYL]AMINO}BENZOIC+ACID'>AOD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Bcep18194_B1568 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36773 Burkholderia sp.])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jum OCA], [https://pdbe.org/3jum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jum RCSB], [https://www.ebi.ac.uk/pdbsum/3jum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jum ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jum OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jum RCSB], [http://www.ebi.ac.uk/pdbsum/3jum PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q396C9_BURL3 Q396C9_BURL3]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/3jum_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/3jum_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jum ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Burkholderia sp]]
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[[Category: Burkholderia lata]]
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[[Category: Blankenfeldt, W]]
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[[Category: Large Structures]]
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[[Category: Breinbauer, R]]
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[[Category: Blankenfeldt W]]
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[[Category: Mentel, M]]
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[[Category: Breinbauer R]]
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[[Category: Biosynthetic protein]]
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[[Category: Mentel M]]
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[[Category: Chirality]]
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[[Category: Drug design]]
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[[Category: Inhibitor]]
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[[Category: Medicinal chemistry]]
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[[Category: Phenazine biosynthesis]]
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Current revision

Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in complex with 5-bromo-2-((1S,3R)-3-carboxycyclohexylamino)benzoic acid

PDB ID 3jum

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