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3jyr

From Proteopedia

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[[Image:3jyr.png|left|200px]]
 
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{{STRUCTURE_3jyr| PDB=3jyr | SCENE= }}
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==Crystal structures of the GacH receptor of Streptomyces glaucescens GLA.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of Salmonella typhimurium.==
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<StructureSection load='3jyr' size='340' side='right'caption='[[3jyr]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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===Crystal structures of the GacH receptor of Streptomyces glaucescens GLA.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of Salmonella typhimurium.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3jyr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JYR FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20132828}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AC1:6-METHYL-5-(4,5,6-TRIHYDROXY-3-HYDROXYMETHYL-CYCLOHEX-2-ENYLAMINO)-TETRAHYDRO-PYRAN-2,3,4-TRIOL'>AC1</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900007:alpha-acarbose'>PRD_900007</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyr OCA], [https://pdbe.org/3jyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jyr RCSB], [https://www.ebi.ac.uk/pdbsum/3jyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jyr ProSAT]</span></td></tr>
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[[3jyr]] is a 1 chain structure of [[Maltose-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYR OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MALE_SALTY MALE_SALTY] Involved in the high-affinity maltose membrane transport system. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jy/3jyr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jyr ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Maltose-binding protein|Maltose-binding protein]]
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*[[Maltose-binding protein 3D structures|Maltose-binding protein 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020132828</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Bulut, H.]]
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[[Category: Bulut H]]
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[[Category: Licht, A.]]
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[[Category: Licht A]]
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[[Category: Schneider, E.]]
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[[Category: Schneider E]]
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[[Category: Vahedi-Faridi, A.]]
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[[Category: Vahedi-Faridi A]]
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[[Category: Abc transporter]]
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[[Category: Acarbose]]
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[[Category: Maltose/maltodextrin-binding protein]]
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[[Category: Salmonella typhimurium]]
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[[Category: Sugar transport]]
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[[Category: Transport]]
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[[Category: Transport protein]]
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Current revision

Crystal structures of the GacH receptor of Streptomyces glaucescens GLA.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of Salmonella typhimurium.

PDB ID 3jyr

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