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3k2z
From Proteopedia
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<StructureSection load='3k2z' size='340' side='right'caption='[[3k2z]], [[Resolution|resolution]] 1.37Å' scene=''> | <StructureSection load='3k2z' size='340' side='right'caption='[[3k2z]], [[Resolution|resolution]] 1.37Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K2Z FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [https://pdbe.org/3k2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [https://www.ebi.ac.uk/pdbsum/3k2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k2z ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [https://pdbe.org/3k2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [https://www.ebi.ac.uk/pdbsum/3k2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k2z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Atcc 43589]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Thermotoga maritima]] |
| - | [[Category: Rice | + | [[Category: Rice PA]] |
| - | [[Category: Zhang | + | [[Category: Zhang APP]] |
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Current revision
Crystal structure of a LexA protein from Thermotoga maritima
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