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3l1e

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{{STRUCTURE_3l1e| PDB=3l1e | SCENE= }}
 
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===Bovine AlphaA crystallin Zinc Bound===
 
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{{ABSTRACT_PUBMED_20440841}}
 
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==Function==
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==Bovine AlphaA crystallin Zinc Bound==
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[[http://www.uniprot.org/uniprot/CRYAA_BOVIN CRYAA_BOVIN]] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
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<StructureSection load='3l1e' size='340' side='right'caption='[[3l1e]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3l1e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The July 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Crystallins'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_7 10.2210/rcsb_pdb/mom_2010_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L1E FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l1e OCA], [https://pdbe.org/3l1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l1e RCSB], [https://www.ebi.ac.uk/pdbsum/3l1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l1e ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CRYAA_BOVIN CRYAA_BOVIN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l1/3l1e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l1e ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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[[3l1e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The July 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Crystallins'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_7 10.2210/rcsb_pdb/mom_2010_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L1E OCA].
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*[[Crystallin 3D structures|Crystallin 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020440841</ref><references group="xtra"/><references/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Crystallins]]
[[Category: Crystallins]]
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[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Cascio, D.]]
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[[Category: Cascio D]]
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[[Category: Eisenberg, D.]]
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[[Category: Eisenberg D]]
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[[Category: Laganowsky, A.]]
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[[Category: Laganowsky A]]
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[[Category: Sawaya, M R.]]
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[[Category: Sawaya MR]]
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[[Category: Chaperone]]
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[[Category: Crystallin]]
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[[Category: Eye lens protein]]
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[[Category: Lens transparency]]
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[[Category: Polydispersity]]
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[[Category: Protein aggregation]]
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Current revision

Bovine AlphaA crystallin Zinc Bound

PDB ID 3l1e

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