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3l40

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{{STRUCTURE_3l40| PDB=3l40 | SCENE= }}
 
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===Crystal Structure of S. pombe Brc1 BRCT5-BRCT6 domains===
 
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{{ABSTRACT_PUBMED_20094029}}
 
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==About this Structure==
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==Crystal Structure of S. pombe Brc1 BRCT5-BRCT6 domains==
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[[3l40]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L40 OCA].
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<StructureSection load='3l40' size='340' side='right'caption='[[3l40]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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== Structural highlights ==
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==Reference==
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<table><tr><td colspan='2'>[[3l40]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L40 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L40 FirstGlance]. <br>
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<ref group="xtra">PMID:020094029</ref><references group="xtra"/><references/>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l40 OCA], [https://pdbe.org/3l40 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l40 RCSB], [https://www.ebi.ac.uk/pdbsum/3l40 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l40 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BRC1_SCHPO BRC1_SCHPO] Required for mitotic fidelity, specifically in the G2 phase of the cell cycle. Plays a role in chromatin organization.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l4/3l40_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l40 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
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[[Category: Guenther, G.]]
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[[Category: Guenther G]]
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[[Category: Tainer, J A.]]
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[[Category: Tainer JA]]
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[[Category: Williams, J S.]]
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[[Category: Williams JS]]
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[[Category: Williams, R S.]]
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[[Category: Williams RS]]
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[[Category: Brc1]]
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[[Category: Brct domain]]
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[[Category: Cell cycle]]
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[[Category: Cell division]]
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[[Category: Dna repair]]
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[[Category: Mitosis]]
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[[Category: Phosphoserine binding domain]]
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[[Category: Tandem brct repeat]]
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Current revision

Crystal Structure of S. pombe Brc1 BRCT5-BRCT6 domains

PDB ID 3l40

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